Rare causes of persistent wheeze that mimic poorly controlled asthma

Asthma and persistent wheeze in the Harvard Six Cities Study.

Cost-effectiveness of bronchial thermoplasty in commercially-insured patients with poorly controlled, severe, persistent asthma.

OBJECTIVES We examined the cost-effectiveness of treating poorly controlled, severe, persistent asthma patients with bronchial thermoplasty (BT), a novel technology that uses thermal energy to reduce airway smooth muscle mass, with 5-year outcome data demonstrating a durable reduction in asthma exacerbations. STUDY DESIGN We conducted a model-based cost-effectiveness analysis assessing 5-year...

Persistent Wheeze Following ACS.

A 70 year-old hypertensive diabetic female from Muscat with a past medical history of a stroke since 9 years ago and is on lisinopril, frusemide and insulin was presented to the emergency room (ER) with dyspnoea which developed three days earlier together with cough and fever. She had attended a local health centre where she was prescribed amoxycillin and erythromycin for community acquired pne...

Optimum predictors of childhood asthma: persistent wheeze or the Asthma Predictive Index?

BACKGROUND The Asthma Predictive Index (API) and persistent wheezing phenotypes are associated with childhood asthma, but previous studies have not assessed their ability to predict objectively confirmed asthma. OBJECTIVE To determine whether the University of Cincinnati API Index (ucAPI) and/or persistent wheezing at age 3 can accurately predict objectively confirmed asthma at age 7. METHO...

Efficacy of esomeprazole for treatment of poorly controlled asthma.

BACKGROUND Gastroesophageal reflux is common among patients with asthma but often causes mild or no symptoms. It is not known whether treatment of gastroesophageal reflux with proton-pump inhibitors in patients who have poorly controlled asthma without symptoms of gastroesophageal reflux can substantially improve asthma control. METHODS In a parallel-group, double-blind trial, we randomly ass...